Emotionally Unstable Personality Disorder (EUPD), also referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional regulation, and can result in impulsive or self-destructive behaviors. Treatment expenses can be significant, with success rates between 35% and 50%. Researchers are investigating alternative therapies to enhance traditional treatment methods.
One notable addition to EUPD management is cannabis, commonly known as weed. Its affordability and beneficial properties can assist patients with EUPD. Those unable to afford multiple therapies may consider cheap cannabis online options for more economical solutions.
Table of Contents
Key Takeaways:
- Individuals with EUPD using THC or high CBD experience favorable outcomes in symptom management.
- Elevated doses of CBD (800 mg/day) and THC flower treatment can boost circulating anandamide levels.
- Dysfunction in the endocannabinoid system, which manages emotions and stress, plays a role in Emotionally Unstable Personality Disorder.
Understanding EUPD or BPD
EUPD is a mental health disorder that influences self-perception and interpersonal relationships, causing challenges in everyday life. It is characterized by volatile relationships, impulsivity, and a skewed self-image.
While the exact origins remain uncertain, factors such as genetics, trauma, and neurotransmitter imbalances could contribute. Dysfunction within the endocannabinoid system, responsible for emotional and stress regulation, may exacerbate EUPD symptoms.
Treatment for EUPD
Even though guidelines indicate that no medications are proven effective for EUPD, clinicians often prescribe drugs like antipsychotics and antidepressants.
Antipsychotic and sedative medications may be beneficial for short-term crisis management or addressing comorbid conditions. A considerable number of patients with EUPD—up to 90% in certain studies—take at least one psychotropic medication, including antipsychotics, antidepressants, mood stabilizers, and sedatives.
Polypharmacy is frequently observed among these individuals. Many of these medications come with side effects and are used off-label for EUPD. While some drugs may alleviate particular symptoms, they do not alter the overall prognosis of the disorder.
Cannabis-Based Medicine for EUPD (CBM)
Cannabis-based medicines are derived from the cannabis plant and include cannabinoids, the active compounds such as tetrahydrocannabinol (THC) and cannabidiol (CBD). These products treat various medical conditions and symptoms, including pain, inflammation, anxiety, seizures, and more.
Numerous studies are currently examining the impacts on mental health. Research published in Frontiers in Psychiatry suggests that marijuana can alleviate depression and improve sleep quality and overall life satisfaction. Such findings support ongoing research into the influence of marijuana on different mental health disorders.
CBM for Unstable Personality Disorder
A narrative review and case series conducted in 2022 indicated that cannabinoids could manage EUPD symptoms in seven patients. Researchers investigate the cellular and molecular mechanisms and evaluate existing evidence for cannabis-based medicinal products (CBMP) as a potential EUPD treatment.
Materials and Methods
Participants were diagnosed with EUPD and had experimented with at least one medication and one form of psychotherapy, along with at least one follow-up at a Zerenia clinic, utilizing patient-reported outcome measures (PROMS).
CBM utilized included dried flower for inhalation (20-60g per month) and oral extracts with THC (9-10mg/day) and CBD (40mg/day), alongside various chemotypes.
Measurement involved the Clinical Global Impression Improvement (CGI-I) Scale and the Patient’s Global Impression of Change (PGIC) Scale, both assessing improvement over time.
Researchers tailored dosing through gradual increases and provided instructions for dose adjustments until satisfactory symptom control was achieved or side effects were noted.
Results
At the one-month follow-up, six participants noted improvements, with five rating their change as a six on the PGIC scale. Only one individual, receiving a chemotype 2 oral extract, reported no benefits, indicating that inhaled tetrahydrocannabinol or higher oral cannabidiol doses may offer better efficacy.
All participants tolerated the treatment well, with no side effects reported, enhancing adherence. Younger individuals might feel more at ease with medical cannabis despite societal stigma.
Hypothesis
Researchers propose that exogenous cannabinoids may help restore the endocannabinoid system’s tonic activation in the central nervous system. THC activates presynaptic CB1 receptors, and both cannabinoids interact with fatty-acid binding proteins (FABPs), potentially slowing the breakdown of anandamide.
High oral cannabidiol doses (800 mg/day) and patients using chemotype 1 flower exhibit elevated circulating anandamide levels. It remains unclear whether this effect stems from cannabidiol’s influence on anandamide transport or degradation or interaction with other molecular targets. In contrast, conventional psychiatric medications typically require 2-3 weeks for initial effects and prolonged periods for remission.
The rapid symptom relief is crucial during an “EUPD crisis,” where distressed individuals may resort to benzodiazepines and other anxiety medications, which can foster rapid tolerance and dependency.
Affordable Cannabis Online for EUPD or BPD
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Manage Behavioural Changes with Bulk Cannabis via Mail-Order Marijuana Service
Cannabinoids effectively manage unstable personality disorders by targeting the endocannabinoid system to regulate anandamide breakdown. Patients with EUPD can benefit from purchasing cannabis online or seeking affordable products to alleviate their symptoms.
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Frequently Asked Questions
Is cheap marijuana of poor quality?
No, price isn’t the only measure of product quality. You can evaluate quality through the product’s physical traits and personal experience. Some dispensaries offer lower prices through monthly or clearance sales. If a dispensary’s prices significantly undercut industry standards, it may raise quality concerns.
Does marijuana have adverse effects when managing BPD?
No adverse effects were reported by study participants. This is critical for ensuring medication adherence, as a review of 36 studies indicated that side effects accounted for 28% of patients’ non-adherence to antipsychotics, while negative perceptions of these medications were a leading cause of intentional non-adherence at 30.5%.
What is the quickest way to feel the effects of cannabinoids for an EUPD issue?
Smoking, vaping, and dabbing are the most rapid methods to feel cannabinoid effects. In the study, participants vaped dried flower. Though smoking and vaping yield similar effects, the distinction lies in inhaling smoke versus vapor. Dabbing, which involves consuming concentrates, also provides a swift onset of effects.
How often can I smoke or vape to manage my symptoms?
The effectiveness of cannabis strains and other products varies based on individual responses. In the study, researchers permitted patients to adjust their daily dosage (between 0.5 and 2 grams per day) without exceeding the monthly limit. For extracts, participants tracked their daily dosages.
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